/usr/lib/pyshared/python2.7/pyspatialite/_spatialite.so is in python-pyspatialite 3.0.1-6.
This file is owned by root:root, with mode 0o777.
It is a symlink to /usr/lib/pyshared/python2.7/pyspatialite/../../../python2.7/dist-packages/pyspatialite/_spatialite.so