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>     1== M63632   1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
--------------------MNGTE--------------------------GDNF-----
---YVP----F-SNKTGLARSPY----------------EYPQY-------YLAEPWK--
-------YSALAAYMFFLILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAMANLFMVLF
G-FTVTMYTSMN-GYFV--FGPTMCSIEGFFATLGGEVALWSLVVLAIERYIVICKPMGN
-FRFGNTHAIMGVAFTWIMALAC-AAPPLVG-W-----SRYIPEGMQCSCGPDYYTLNPN
FNNESYVVYMFVVHFLVPFVIIFFCYGRLLCTV----KEAAAAQQ---------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------ESASTQKAEKEVTRMVVLMVIGFLVCWVPYASV
AFYIFTHQGS---DFGATFMTLPAFFAKSSALYNPVIYILMNKQFRNCMITTLCC-----
--GKNPLGD-DE--SGASTSKTEVSSVS--TSPV--------------------------
----------------------------------------------SPA-----------
---
>     2== U22180   1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
--------------------MNGTE--------------------------GPNF-----
---YVP----F-SNITGVVRSPF----------------EQPQY-------YLAEPWQ--
-------FSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFG
G-FTTTLYTSLH-GYFV--FGPTGCNLEGFFATLGGEIGLWSLVVLAIERYVVVCKPMSN
-FRFGENHAIMGVAFTWVMALAC-AAPPLVG-W-----SRYIPEGMQCSCGIDYYTLKPE
VNNESFVIYMFVVHFTIPMIVIFFCYGQLVFTV----KEAAAQQQ---------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------ESATTQKAEKEVTRMVIIMVIFFLICWLPYASV
AMYIFTHQGS---NFGPIFMTLPAFFAKTASIYNPIIYIMMNKQFRNCMLTSLCC-----
--GKNPLGD-DE--ASATASKTE-------TSQV--------------------------
----------------------------------------------APA-----------
---
>     3== M92038   1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
--------------------MNGTE--------------------------GINF-----
---YVP----M-SNKTGVVRSPF----------------EYPQY-------YLAEPWK--
-------YRLVCCYIFFLISTGLPINLLTLLVTFKHKKLRQPLNYILVNLAVADLFMACF
G-FTVTFYTAWN-GYFV--FGPVGCAVEGFFATLGGQVALWSLVVLAIERYIVVCKPMGN
-FRFSATHAMMGIAFTWVMAFSC-AAPPLFG-W-----SRYMPEGMQCSCGPDYYTHNPD
YHNESYVLYMFVIHFIIPVVVIFFSYGRLICKV----REAAAQQQ---------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------ESATTQKAEKEVTRMVILMVLGFMLAWTPYAVV
AFWIFTNKGA---DFTATLMAVPAFFSKSSSLYNPIIYVLMNKQFRNCMITTICC-----
--GKNPFGD-EDVSSTVSQSKTEVSSVS--SSQV--------------------------
----------------------------------------------SPA-----------
---
>     4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
--------------------MNGTE--------------------------GKNF-----
---YVP----M-SNRTGLVRSPF----------------EYPQY-------YLAEPWQ--
-------FKILALYLFFLMSMGLPINGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVCF
G-FTVTFYTAIN-GYFV--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS
-FKFSSSHAFAGIAFTWVMALAC-AAPPLFG-W-----SRYIPEGMQCSCGPDYYTLNPD
YNNESYVIYMFVCHFILPVAVIFFTYGRLVCTV----KAAAAQQQ---------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------DSASTQKAEREVTKMVILMVFGFLIAWTPYATV
AAWIFFNKGA---DFSAKFMAIPAFFSKSSALYNPVIYVLLNKQFRNCMLTTIFC-----
--GKNPLGD-DE-SSTVSTSKTEVSS-------V--------------------------
----------------------------------------------SPA-----------
---
>     5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
--------------------MNGTE--------------------------GNNF-----
---YVP----L-SNRTGLVRSPF----------------EYPQY-------YLAEPWQ--
-------FKLLAVYMFFLICLGLPINGLTLICTAQHKKLRQPLNFILVNLAVAGAIMVCF
G-FTVTFYTAIN-GYFA--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS
-FKFSSTHASAGIAFTWVMAMAC-AAPPLVG-W-----SRYIPEGIQCSCGPDYYTLNPE
YNNESYVLYMFICHFILPVTIIFFTYGRLVCTV----KAAAAQQQ---------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------DSASTQKAEREVTKMVILMVLGFLVAWTPYATV
AAWIFFNKGA---AFSAQFMAIPAFFSKTSALYNPVIYVLLNKQFRSCMLTTLFC-----
--GKNPLGD-EE-SSTVSTSKTEVSS-------V--------------------------
----------------------------------------------SPA-----------
---
>     6== L11864   1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
--------------------MKQVPEF------------------------HEDF-----
---YIPIPLDI-NNLS--AYSPF----------------LVPQD-------HLGNQGI--
-------FMAMSVFMFFIFIGGASINILTILCTIQFKKLRSHLNYILVNLSIANLFVAIF
G-SPLSFYSFFN-RYFI--FGATACKIEGFLATLGGMVGLWSLAVVAFERWLVICKPLGN
-FTFKTPHAIAGCILPWISALAA-SLPPLFG-W-----SRYIPEGLQCSCGPDWYTTNNK
YNNESYVMFLFCFCFAVPFGTIVFCYGQLLITL----KLAAKAQA---------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------DSASTQKAEREVTKMVVVMVLGFLVCWAPYASF
SLWIVSHRGE---EFDLRMATIPSCLSKASTVYNPVIYVLMNKQFRSCMM-KMVC-----
--GKN-IEE-DE--ASTSSQVTQVSS-------V--------------------------
----------------------------------------------APEK----------
---
>     7== M13299   1 human BCP <>[Science232(4747),193-202'86]
--------------------MRKMS--------------------------EEEF-----
---YL-----F-KNIS--SVGPW----------------DGPQY-------HIAPVWA--
-------FYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIF
S-VFPVFVASCN-GYFV--FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGN
-FRFSSKHALTVVLATWTIGIGV-SIPPFFG-W-----SRFIPEGLQCSCGPDWYTVGTK
YRSESYTWFLFIFCFIVPLSLICFSYTQLLRAL----KAVAAQQQ---------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------ESATTQKAEREVSRMVVVMVGSFCVCYVPYAAF
AMYMVNNRNH---GLDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIM-KMVC-----
--GKA-MTD-ES--DTCSSQKTEVSTVS--STQV--------------------------
----------------------------------------------GPN-----------
---
>     8=opsin, greensensitive  human (fragment) S07060
------------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------DLAETVI
A-STISIVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN
-VRFDAKLAIVGIAFSWIWAAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSY
PGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAI----RAVAKQQK---------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------ESESTQKAEKEVTRMVVVMVLAFC---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
---
>     9== K03494   1 human GCP <>[Science232(4747),193-202'86]
--------------------MAQQWSL------------QRLAGRHPQDSYEDST-----
---QSSI-FTY-TNSNS-TRGPF----------------EGPNY-------HIAPRWV--
-------YHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVI
A-STISVVNQVY-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGN
-VRFDAKLAIVGIAFSWIWAAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSY
PGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAI----RAVAKQQK---------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------ESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFF
ACFAAANPGY---PFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCIL-QLF------
--GKK-VDD-GS--ELSSASKTEVSSV----SSV--------------------------
----------------------------------------------SPA-----------
---
>    10== Z68193   1 human Red Opsin <>[]
--------------------MAQQWSL------------QRLAGRHPQDSYEDST-----
---QSSI-FTY-TNSNS-TRGPF----------------EGPNY-------HIAPRWV--
-------YHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVI
A-STISIVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN
-VRFDAKLAIVGIAFSWIWSAVW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSY
PGVQSYMIVLMVTCCIIPLAIIMLCYLQVWLAI----RAVAKQQK---------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------ESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFF
ACFAAANPGY---AFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCIL-QLF------
--GKK-VDD-GS--ELSSASKTEVSSV----SSV--------------------------
----------------------------------------------SPA-----------
---
>    11== M92036   1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
--------------------MTEAWNV------------AVFAARRSRDD-DDTT-----
---RGSV-FTY-TNTNN-TRGPF----------------EGPNY-------HIAPRWV--
-------YNLVSFFMIIVVIASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVDLVETLV
A-STISVFNQIF-GYFI--LGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVVCKPFGN
-IKFDSKLAIIGIVFSWVWAWGW-SAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSVE
LGCQSFMLTLMITCCFLPLFIIIVCYLQVWMAI----RAVAAQQK---------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------ESESTQKAEREVSRMVVVMIVAFCICWGPYASF
VSFAAANPGY---AFHPLAAALPAYFAKSATIYNPVIYVFMNRQFRNCIM-QLF------
--GKK-VDD-GS--EASTTSRTEVSSVS--NSSV--------------------------
----------------------------------------------APA-----------
---
>    12== M62903   1 chicken visual pigment <>[BBRC173,1212-1217'90]
--------------------MA-AWEA------------AFAARRRHEE--EDTT-----
---RDSV-FTY-TNSNN-TRGPF----------------EGPNY-------HIAPRWV--
-------YNLTSVWMIFVVAASVFTNGLVLVATWKFKKLRHPLNWILVNLAVADLGETVI
A-STISVINQIS-GYFI--LGHPMCVVEGYTVSACGITALWSLAIISWERWFVVCKPFGN
-IKFDGKLAVAGILFSWLWSCAW-TAPPIFG-W-----SRYWPHGLKTSCGPDVFSGSSD
PGVQSYMVVLMVTCCFFPLAIIILCYLQVWLAI----RAVAAQQK---------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------ESESTQKAEKEVSRMVVVMIVAYCFCWGPYTFF
ACFAAANPGY---AFHPLAAALPAYFAKSATIYNPIIYVFMNRQFRNCIL-QLF------
--GKK-VDD-GS--EVST-SRTEVSSVS--NSSV--------------------------
----------------------------------------------SPA-----------
---
>    13== S75720   1 chicken P-opsin <>[Science267(5203),1502-1506'95]
--------------------MSSNSSQA-----------------------PPNG-----
------------------TPGPF----------------DGPQW------PYQAPQST--
-------YVGVAVLMGTVVACASVVNGLVIVVSICYKKLRSPLNYILVNLAVADLLVTLC
G-SSVSLSNNIN-GFFV--FGRRMCELEGFMVSLTGIVGLWSLAILALERYVVVCKPLGD
-FQFQRRHAVSGCAFTWGWALLW-SAPPLLG-W-----SSYVPEGLRTSCGPNWYTGGS-
-NNNSYILSLFVTCFVLPLSLILFSYTNLLLTL----RAAAAQQK---------------
------------------------------------------------------------
------------------------------------------------------------
---------------------------EADTTQRAEREVTRMVIVMVMAFLLCWLPYSTF
ALVVATHKGI---IIQPVLASLPSYFSKTATVYNPIIYVFMNKQFQSCLLEMLCCGYQPQ
RTGKA--------SPGTPGPHADVTAAGL-RNKV--------------------------
----------------------------------------------MPAHPV--------
---
>    14== M17718   1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
-----MESGNVSS-----SLFGNVSTA-------------LRPEARL----SAET-----
------RLLGW--------NVPP----------------EELR--------HIPEHWLTY
PEPPESMNYLLGTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMVK
--TPIFIYNSFH-QGYA--LGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEG
--KMTHGKAIAMIIFIYMYATPW-VVACYTETW-----GRFVPEGYLTSCTFDYLT--DN
FDTRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKK--------------
------------------------------------------------------------
--------------------------------------MNVESL----------------
------------------RS------NVDKNKETAEIRIAKAAITICFLFFCSWTPYGVM
SLIGAFGDKT---LLTPGATMIPACACKMVACIDPFVYAISHPRYRMELQKRCPWLAL--
----NEKAP-ES-SAVASTSTTQEPQQ---TTAA--------------------------
------------------------------------------------------------
---
>    15== X65879   1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
-----MEYHNVS------SVLGNVSSV-------------LRPDARL----SAES-----
------RLLGW--------NVPP----------------DELR--------HIPEHWLIY
PEPPESMNYLLGTLYIFFTVISMIGNGLVMWVFSAAKSLRTPSNILVINLAFCDFMMMIK
--TPIFIYNSFH-QGYA--LGHLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVITRPMEG
--KMTHGKAIAMIIFIYLYATPW-VVACYTESW-----GRFVPEGYLTSCTFDYLT--DN
FDTRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKK--------------
------------------------------------------------------------
--------------------------------------MNVDSL----------------
------------------RS------NVDKSKEAAEIRIAKAAITICFLFFASWTPYGVM
SLIGAFGDKT---LLTPGATMIPACTCKMVACIDPFVYAISHPRYRMELQKRCPWLAI--
----SEKAP-ES-RAAISTSTTQEQQQ---TTAA--------------------------
------------------------------------------------------------
---
>    16== M17730   1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
-----MEP------------LCNASEP------------PLRPEAR--SSGNGDL-----
------QFLGW--------NVPP----------------DQIQ--------YIPEHWLTQ
LEPPASMHYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK
--APIF--NSFH-RGFAIYLGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR
--NMTFTKAVIMNIIIWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDYLS--DN
FDTRLFVGTIFFFSFVCPTLMILYYYSQIVGHVFSHEKALREQAKK--------------
------------------------------------------------------------
--------------------------------------MNVESL----------------
------------------RS------NVDKSKETAEIRIAKAAITICFLFFVSWTPYGVM
SLIGAFGDKS---LLTQGATMIPACTCKLVACIDPFVYAISHPRYRLELQKRCPWLGV--
----NEKSG-EI-SSAQSTTTQEQQQ----TTAA--------------------------
------------------------------------------------------------
---
>    17== X65880   1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
-----MDA------------LCNASEP------------PLRPEARM-SSGSDEL-----
------QFLGW--------NVPP----------------DQIQ--------YIPEHWLTQ
LEPPASMHYMLGVFYIFLFFASTLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK
--APIFIYNSFH-RGFA--LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR
--NMTFTKAVIMNIIIWLYCTPW-VVLPLTQFW-----DRFVPEGYLTSCSFDYLS--DN
FDTRLFVGTIFLFSFVVPTLMILYYYSQIVGHVFNHEKALREQAKK--------------
------------------------------------------------------------
--------------------------------------MNVESL----------------
------------------RS------NVDKSKETAEIRIAKAAITICFLFFVSWTPYGVM
SLIGAFGDKS---LLTPGATMIPACTCKLVACIEPFVYAISHPRYRMELQKRCPWLGV--
----NEKSG-EA-SSAQSTTTQEQTQQ---TSAA--------------------------
------------------------------------------------------------
---
>    18== D50584   1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
--------------------MTNATGP------------QMAYYGAA----SMD------
--------FGYPEGVSIVDFVRP----------------EIKP--------YVHQHWYNY
PPVNPMWHYLLGVIYLFLGTVSIFGNGLVIYLFNKSAALRTPANILVVNLALSDLIMLTT
N-VPFFTYNCFSGGVWM--FSPQYCEIYACLGAITGVCSIWLLCMISFDRYNIICNGFNG
-PKLTTGKAVVFALISWVIAIGC-ALPPFFG-W-----GNYILEGILDSCSYDYLT--QD
FNTFSYNIFIFVFDYFLPAAIIVFSYVFIVKAIFAHEAAMRAQAKK--------------
------------------------------------------------------------
--------------------------------------MNVSTL----------------
------------------RS-------NEADAQRAEIRIAKTALVNVSLWFICWTPYALI
SLKGVMGDTS---GITPLVSTLPALLAKSCSCYNPFVYAISHPKYRLAITQHLPWFCV--
--HETETKS-ND-DSQSNSTVAQDKA----------------------------------
------------------------------------------------------------
---
>    19== D50583   1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
--------------------MANVTGP------------QMAFYGSG----AAT------
--------FGYPEGMTVADFVPD----------------RVKH--------MVLDHWYNY
PPVNPMWHYLLGVVYLFLGVISIAGNGLVIYLYMKSQALKTPANMLIVNLALSDLIMLTT
N-FPPFCYNCFSGGRWM--FSGTYCEIYAALGAITGVCSIWTLCMISFDRYNIICNGFNG
-PKLTQGKATFMCGLAWVISVGW-SLPPFFG-W-----GSYTLEGILDSCSYDYFT--RD
MNTITYNICIFIFDFFLPASVIVFSYVFIVKAIFAHEAAMRAQAKK--------------
------------------------------------------------------------
--------------------------------------MNVTNL----------------
------------------RS-------NEAETQRAEIRIAKTALVNVSLWFICWTPYAAI
TIQGLLGNAE---GITPLLTTLPALLAKSCSCYNPFVYAISHPKFRLAITQHLPWFCV--
--HEKDPND-VE-ENQSSNTQTQEKS----------------------------------
------------------------------------------------------------
---
>    20== K02320   1 D.melanogaster opsin <>[Cell40,851-858'85]
-----MESFA---------VAAAQLGP------------HFAPLS---------------
-------------NGSVVDKVTP----------------DMAH--------LISPYWNQF
PAMDPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMIT
N-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG
-RPMTIPLALGKM---------------------------YVPEGNLTSCGIDYLE--RD
WNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKK--------------
------------------------------------------------------------
--------------------------------------MNVKSL----------------
------------------RS-------SEDAEKSAEGKLAKVALVTITLWFMAWTPYLVI
NCMGLFKF-E---GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF--
--GKVDDGK-SS-DAQSQATASEAESKA--------------------------------
------------------------------------------------------------
---
>    21== K02315   1 D.melanogaster ninaE <>[Cell40,839-850'85]
-----MESFA---------VAAAQLGP------------HFAPLS---------------
-------------NGSVVDKVTP----------------DMAH--------LISPYWNQF
PAMDPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMIT
N-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG
-RPMTIPLALGKIAYIWFMSSIW-CLAPAFG-W-----SRYVPEGNLTSCGIDYLE--RD
WNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKK--------------
------------------------------------------------------------
--------------------------------------MNVKSL----------------
------------------RS-------SEDAEKSAEGKLAKVALVTITLWFMAWTPYLVI
NCMGLFKF-E---GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF--
--GKVDDGK-SS-DAQSQATASEAESKA--------------------------------
------------------------------------------------------------
---
>    22== X65877   1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
-----MDSFA---------AVATQLGP------------QFAAPS---------------
-------------NGSVVDKVTP----------------DMAH--------LISPYWDQF
PAMDPIWAKILTAYMIIIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMIT
N-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG
-RPMTIPLALGKIAYIWFMSTIWCCLAPVFG-W-----SRYVPEGNLTSCGIDYLE--RD
WNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKK--------------
------------------------------------------------------------
--------------------------------------MNVKSL----------------
------------------RS-------SEDADKSAEGKLAKVALVTISLWFMAWTPYLVI
NCMGLFKF-E---GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCVF--
--GKVDDGK-SS-EAQSQATTSEAESKA--------------------------------
------------------------------------------------------------
---
>    23== M12896   1 D.melanogaster Rh2 <>[Cell44,705-710'86]
MERSHLPETP---------FDLAHSGP------------RFQAQSSG-------------
-------------NGSVLDNVLP----------------DMAH--------LVNPYWSRF
APMDPMMSKILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMAS
Q-SPVMIINFYY-ETWV--LGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGING
-TPMTIKTSIMKILFIWMMAVFW-TVMPLIG-W-----SAYVPEGNLTACSIDYMT--RM
WNPRSYLITYSLFVYYTPLFLICYSYWFIIAAVAAHEKAMREQAKK--------------
------------------------------------------------------------
--------------------------------------MNVKSL----------------
------------------RS-------SEDCDKSAEGKLAKVALTTISLWFMAWTPYLVI
CYFGLFKI-D---GLTPLTTIWGATFAKTSAVYNPIVYGISHPKYRIVLKEKCPMCVF--
--GNTDEPKPDA-PASDTETTSEADSKA--------------------------------
------------------------------------------------------------
---
>    24== X65878   1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
MERSLLPEPP---------LAMALLGP------------RFEAQTGG-------------
-------------NRSVLDNVLP----------------DMAP--------LVNPHWSRF
APMDPTMSKILGLFTLVILIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMAS
Q-SPVMIINFYY-ETWV--LGPLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVIVKGING
-TPMTIKTSIMKIAFIWMMAVFW-TIMPLIG-W-----SSYVPEGNLTACSIDYMT--RQ
WNPRSYLITYSLFVYYTPLFMICYSYWFIIATVAAHEKAMRDQAKK--------------
------------------------------------------------------------
--------------------------------------MNVKSL----------------
------------------RS-------SEDCDKSAENKLAKVALTTISLWFMAWTPYLII
CYFGLFKI-D---GLTPLTTIWGATFAKTSAVYNPIVYGISHPNDRLVLKEKCPMCVC--
--GTTDEPKPDA-PPSDTETTSEAESKD--------------------------------
------------------------------------------------------------
---
>    25== U26026   1 Apis mellifera long-wavelength rhodopsin <>[]
--------------------MIAVSGP------------SYEAFSYG---GQARF-----
------------NNQTVVDKVPP----------------DMLH--------LIDANWYQY
PPLNPMWHGILGFVIGMLGFVSAMGNGMVVYIFLSTKSLRTPSNLFVINLAISNFLMMFC
M-SPPMVINCYY-ETWV--LGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKGLSG
-KPLSINGALIRIIAIWLFSLGW-TIAPMFG-W-----NRYVPEGNMTACGTDYFN--RG
LLSASYLVCYGIWVYFVPLFLIIYSYWFIIQAVAAHEKNMREQAKK--------------
------------------------------------------------------------
--------------------------------------MNVASL----------------
------------------RS-------SENQNTSAECKLAKVALMTISLWFMAWTPYLVI
NFSGIFNL-V---KISPLFTIWGSLFAKANAVYNPIVYGISHPKYRAALFAKFPSLAC--
---AAEPSS-DA-VSTTSGTTTVTDNEK--SNA---------------------------
------------------------------------------------------------
---
>    26== L03781   1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
--------------------MAN----------------QLSYSSLG-------------
--------WPYQPNASVVDTMPK----------------EMLY--------MIHEHWYAF
PPMNPLWYSILGVAMIILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAF
M-MPTMTSNCFA-ETWI--LGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAA
-APLTHKKATLLLLFVWIWSGGW-TILPFFG-W-----SRYVPEGNLTSCTVDYLT--KD
WSSASYVVIYGLAVYFLPLITMIYCYFFIVHAVAEHEKQLREQAKK--------------
------------------------------------------------------------
--------------------------------------MNVASL----------------
------------------RA------NADQQKQSAECRLAKVAMMTVGLWFMAWTPYLII
SWAGVFSSGT---RLTPLATIWGSVFAKANSCYNPIVYGISHPRYKAALYQRFPSLAC--
--GSGESGS-DV-KSEASATTTMEEKPK--------------------------------
----------------------------------------------IPEA----------
---
>    27== X07797   1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
--------------------MVESTTL-----------------------VNQTW-----
----------W-YNPTV----------------------------------DIHPHWAKF
DPIPDAVYYSVGIFIGVVGIIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSAI
NGFPLKTISAFM-KKWI--FGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMAA
SKKMSHRRAFLMIIFVWMWSIVW-SVGPVFN-W-----GAYVPEGILTSCSFDYLS--TD
PSTRSFILCMYFCGFMLPIIIIAFCYFNIVMSVSNHEKEMAAMAKR--------------
------------------------------------------------------------
--------------------------------------LNAKEL----------------
------------------R--------KAQAGASAEMKLAKISMVIITQFMLSWSPYAII
ALLAQFGPAE---WVTPYAAELPVLFAKASAIHNPIVYSVSHPKFREAIQTTFPWLLTCC
QFDEKECED-AN-DAEEEVVASERGGES--RDAAQMKEMMAMMQKMQAQQAAYQPPPPPQ
GY--PPQGYPPQGAYPPPQGYPPQGYPPQGYPPQGYPPQGAPPQVEAPQGAPPQGVDNQA
YQA
>    28== X70498   1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
--------------------MGRDLRD------------------------NETW-----
----------W-YNPSI----------------------------------VVHPHWREF
DQVPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLV
NGFPLMTISCFL-KKWI--FGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAA
SKKMSHRRAFIMIIFVWLWSVLW-AIGPIFG-W-----GAYTLEGVLCNCSFDYIS--RD
STTRSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKEMAAMAKR--------------
------------------------------------------------------------
--------------------------------------LNAKEL----------------
------------------R--------KAQAGANAEMRLAKISIVIVSQFLLSWSPYAVV
ALLAQFGPLE---WVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCC
QFDDKETED-DK-DAETEIPAGESSDAAPSADAAQMKEMMAMMQKMQQQQAAY----PPQ
GYAPPPQGYPPQGY--PPQGYPPQGYPPQGYPP---PPQGAPPQ-GAPPAAPPQGVDNQA
YQA
>    29== L21195   1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
--------------------MMDVNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPV
AGSWAPHLLS---EVTASPAPTW----------------DAPPDNASGCGEQIN------
--YGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVA
V-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTY
PVRQNGKCMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF------
----GYTIYSTAVAFYIPMSVMLFMYYQIY-------KAARKSAAKHKF-----------
----------------------PGF-----------------PRVEPDSVIAL-------
--------NGIVKLQKEV--------------------EECANLSRLLKH----------
-----------------ER--------KNISIFKREQKAATTLGIIVGAFTVCWLPFFLL
STARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNI
--NRKLSAA-GMHEALKLAERPERPEFVL-QNADYCRK----------------------
----------------------------KGHDS---------------------------
---
>    30== L15228   1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
--------------------M---------------------------------------
-----PHLLSGFLEVTASPAPTW----------------DAPPDNVSGCGEQIN------
--YGRVEKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVA
V-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTY
PVRQNGKCMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF------
----GYTIYSTAVAFYIPMSVMLFMYYQIY-------KAARKSAAKHKF-----------
----------------------PGF-----------------PRVQPESVISL-------
--------NGVVKLQKEV--------------------EECANLSRLLKH----------
-----------------ER--------KNISIFKREQKAATTLGIIVGAFTVCWLPFFLL
STARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRPTSRSLLQCQYRNI
--NRKLSAA-GMHEALKLAERPERSEFVL-QNSDHCGK----------------------
----------------------------KGHDT---------------------------
---
>    31=p A47425 serotonin receptor 5HT-7 - rat
--------------------M---------------------------------------
-----PHLLSGFLEVTASPAPTW----------------DAPPDNVSGCGEQIN------
--YGRVEKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVA
V-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTY
PVRQNGKCMAKMILSVWLLSASI-TLPPLFG-W-----AQNVNDDKVCLISQDF------
----GYTIYSTAVAFYIPMSVMLFMYYQIY-------KAARKSAAKHKF-----------
----------------------PGF-----------------PRVQPESVISL-------
--------NGVVKLQKEV--------------------EECANLSRLLKH----------
-----------------ER--------KNISIFKREQKAATTLGIIVGAFTVCWLPFFLL
STARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNI
--NRKLSAA-GMHEALKLAERPERSEFVL-QNSDHCGK----------------------
----------------------------KGHDT---------------------------
---
>    32== M83181   1 human serotonin receptor <>[JBC267(11),7553-7562'92]
-----MDVLSPGQ-------GNNTTSPPA----------PFETGG---------------
-------------NTTGISDVTV-------------------------------------
-----SYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVL
V-LPMAALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDY
VNKRTPRRAAALISLTWLIGFLI-SIPPMLG-WRTPE-DRSDPDA--CTISKDH------
----GYTIYSTFGAFYIPLLLMLVLYGRIF-------RAARFRIRK--------------
-------------------------TVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNW
RLGVESKAGGALCANGAVRQG-----------------DDGAALEVIEVHRVGNSKEHLP
LPSEAGPTPCA--PASFERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIV
ALVLPFCESS-C-HMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRQ
------------------------------------------------------------
------------------------------------------------------------
---
>    33=p A35181 serotonin receptor class 1A - rat
-----MDVFSFGQ-------GNNTTASQE----------PFGTGG---------------
-------------NVTSISDVTF-------------------------------------
-----SYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVL
V-LPMAALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDY
VNKRTPRRAAALISLTWLIGFLI-SIPPMLG-WRTPE-DRSDPDA--CTISKDH------
----GYTIYSTFGAFYIPLLLMLVLYGRIF-------RAARFRIRK--------------
-------------------------TVRKVEKKGAGTSLGTSSAPPPKKSLNGQPGSGDW
RRCAENRAVGTPCTNGAVRQG-----------------DDEATLEVIEVHRVGNSKEHLP
LPSESGSNSYA--PACLERKNERNAEAKRKMALARERKTVKTLGIIMGTFILCWLPFFIV
ALVLPFCESS-C-HMPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIKCKFCRR
------------------------------------------------------------
------------------------------------------------------------
---
>    34== L06803   1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
-----MANFTFGDLALDVARMGGLASTPS----------GLRSTGLTTPGLSPTG-----
-------------LVTSDFNDSYGLTGQFINGSHSSRSRDNASANDTSATNMTDDRYWSL
TVYSHEHLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVL
V-MPLSVVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDY
IRRRSARRILLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK------
----GYTIFSTVGAFYLPMLVMMIIYIRIW-------LVARSRIRKDKFQMTKARLKTEE
TTLVASPKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPEN--
-------ANGVNSNSSSS-ER-LKQIQIETAEAFANGCAEEASIAMLERQ-CNNGKKISS
NDTPYS------------RT-------REKLELKRERKAARTLAIITGAFLICWLPFFII
ALIGPFVDPE---GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILFGKYR--
------------------------------------------------------------
-------------------------------------------------RGHR-------
---
>    35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
-----MANFTFGDLALDVARMGGLASTPS----------GLRSTGLTTPGLSPTG-----
-------------LVTSDFNDSYGLTGQFINGSHSSRSRDNASANDTSATNMTDDRYWSL
TVYSHEHLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVL
V-MPLSVVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDY
IRRRSARRILLMIMVVWIVALFI-SIPPLFG-WRDP--NNDPDKTGTCIISQDK------
----GYTIFSTVGAFYLPMLVMMIIYIRIW-------LVARSRIRKDKFQMTKARLKTEE
TTLVASPKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPEN--
-------ANGVNSNSSSS-ER-LKQIQIETAEAFANGCAEEASIAMLERQ-CNNGKKISS
NDTPYS------------RT-------REKLELKRERKAARTLAIITGAFLICWLPFFII
ALIGPFVDPE---GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILFGKYR--
------------------------------------------------------------
-------------------------------------------------RGHR-------
---
>    36== X95604   1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
--------------------MEGAEGQEELDWEALYLRLPLQNCSWNSTGWEPNW-----
-------------NVTVVPNTTW---------WQASAPFDTPAAL---------------
-----VRAAAKAVVLGLLILATVVGNVFVIAAILLERHLRSAANNLILSLAVADLLVACL
V-MPLGAVYEVV-QRWT--LGPELCDMWTSGDVLCCTASILHLVAIALDRYWAVTN-IDY
IHASTAKRVGMMIACVWTVSFFV-CIAQLLG-WKDPDWNQRVSEDLRCVVSQDV------
----GYQIFATASSFYVPVLIILILYWRIY-------QTARKRIRR--------------
-------------------------------RRGATARGGVGPPPVPAGG-ALVAGGG--
-------SGGIAAAVVAVIGRPLPTISETTTTGFTNVSSNNTSP---EKQSCANGLEADP
PTTGYGAVAAAYYPSLVRRKP------KEAADSKRERKAAKTLAIITGAFVACWLPFFVL
AILVPTCDCE----VSPVLTSLSLWLGYFNSTLNPVIYTVFSPEFRHAFQRLLCGRRVRR
R-----------------------------------------------------------
---------------------------------------------RAPQ-----------
---