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# BioPerl module for Bio::Map::MapI
#
# Please direct questions and support issues to <bioperl-l@bioperl.org>
#
# Cared for by Sendu Bala <bix@sendu.me.uk>
#
# Copyright Jason Stajich
#
# You may distribute this module under the same terms as perl itself
# POD documentation - main docs before the code
=head1 NAME
Bio::Map::MapI - Interface for describing Map objects in bioperl
=head1 SYNOPSIS
# get a MapI somehow
my $name = $map->name(); # string
my $length = $map->length(); # integer
my $species= $map->species; # Bio::Species
my $type = $map->type(); # genetic/sts/rh/
=head1 DESCRIPTION
This object describes the basic functionality of a Map in bioperl.
Maps are anything from Genetic Map to Sequence Map to Assembly Map
to Restriction Enzyme to FPC.
=head1 FEEDBACK
=head2 Mailing Lists
User feedback is an integral part of the evolution of this and other
Bioperl modules. Send your comments and suggestions preferably to
the Bioperl mailing list. Your participation is much appreciated.
bioperl-l@bioperl.org - General discussion
http://bioperl.org/wiki/Mailing_lists - About the mailing lists
=head2 Support
Please direct usage questions or support issues to the mailing list:
I<bioperl-l@bioperl.org>
rather than to the module maintainer directly. Many experienced and
reponsive experts will be able look at the problem and quickly
address it. Please include a thorough description of the problem
with code and data examples if at all possible.
=head2 Reporting Bugs
Report bugs to the Bioperl bug tracking system to help us keep track
of the bugs and their resolution. Bug reports can be submitted via the
web:
https://github.com/bioperl/bioperl-live/issues
=head1 AUTHOR - Jason Stajich
Email jason@bioperl.org
=head1 CONTRIBUTORS
Lincoln Stein, lstein@cshl.org
Heikki Lehvaslaiho, heikki-at-bioperl-dot-org
Sendu Bala, bix@sendu.me.uk
=head1 APPENDIX
The rest of the documentation details each of the object methods.
Internal methods are usually preceded with a _
=cut
# Let the code begin...
package Bio::Map::MapI;
use strict;
use Bio::Map::PositionHandler;
use base qw(Bio::Map::EntityI Bio::AnnotatableI);
=head2 EntityI methods
These are fundamental to coordination of Maps and other entities, so are
implemented at the interface level
=cut
=head2 get_position_handler
Title : get_position_handler
Usage : my $position_handler = $entity->get_position_handler();
Function: Gets a PositionHandlerI that $entity is registered with.
Returns : Bio::Map::PositionHandlerI object
Args : none
=cut
sub get_position_handler {
my $self = shift;
unless (defined $self->{_eh}) {
my $ph = Bio::Map::PositionHandler->new(-self => $self);
$self->{_eh} = $ph;
$ph->register;
}
return $self->{_eh};
}
=head2 PositionHandlerI-related methods
These are fundamental to coordination of Maps and other entities, so are
implemented at the interface level
=cut
=head2 get_positions
Title : get_positions
Usage : my @positions = $mappable->get_positions();
Function: Get all the Positions on this Map (sorted).
Returns : Array of L<Bio::Map::PositionI> objects
Args : none for all, OR
L<Bio::Map::MappableI> object for positions of the given Mappable
=cut
sub get_positions {
my ($self, $mappable) = @_;
my @positions = $self->get_position_handler->get_positions($mappable);
# precompute sortable for effieciency and to avoid bugs
@positions = map { $_->[1] }
sort { $a->[0] <=> $b->[0] }
map { [$_->sortable, $_] }
@positions;
return @positions;
}
=head2 each_position
Title : each_position
Function: Synonym of the get_positions() method.
Status : deprecated, will be removed in next version
=cut
*each_position = \&get_positions;
=head2 purge_positions
Title : purge_positions
Usage : $map->purge_position();
Function: Remove all positions from this map. Notifies the positions they are
no longer on this map.
Returns : n/a
Args : none to remove all positions, OR
L<Bio::Map::PositionI> object to remove just that Position, OR
L<Bio::Map::MappableI> object to remove only those positions of the
given mappable
=cut
sub purge_positions {
my ($self, $thing) = @_;
$self->get_position_handler->purge_positions($thing);
}
=head2 get_elements
Title : get_elements
Usage : my @elements = $map->get_elements;
Function: Retrieves all the elements on a map (unordered)
Returns : Array of Map elements (L<Bio::Map::MappableI>)
Args : none
=cut
sub get_elements {
my $self = shift;
return $self->get_position_handler->get_other_entities;
}
=head2 each_element
Title : each_element
Function: Synonym of the get_elements() method.
Status : deprecated, will be removed in the next version
=cut
=head2 common_elements
Title : common_elements
Usage : my @common_elements = $map->common_elements(\@other_maps);
my @common_elements = Bio::Map::SimpleMap->common_elements(\@maps);
Function: Find the elements that are common to multiple maps.
Returns : array of Bio::Map::MappableI
Args : arg #1 = L<Bio::Map::MapI> to compare this one to, or an array ref
of such objects (mandatory)
arg #2 = optionally, one or more of the key => value pairs below
-min_num => int : the minimum number of input maps an element
must be found on before before returned
[default is 1]
-min_percent => number : as above, but the minimum percentage of
input maps [default is 100 - note that this
will effectively override all other options]
-require_self => 1|0 : require that all output elements at least
be on the calling map [default is 1, has no
effect when the second usage form is used]
-required => \@maps : require that all output elements be on at
least all the maps supplied here
=cut
sub common_elements {
my ($self, $maps_ref, @extra_args) = @_;
$self->throw("Must supply a reference first argument") unless ref($maps_ref);
my @maps;
if (ref($maps_ref) eq 'ARRAY') {
@maps = @{$maps_ref};
}
elsif ($maps_ref->isa('Bio::Map::MapI')) {
@maps = ($maps_ref);
}
if (ref($self)) {
unshift(@maps, $self);
}
$self->throw("Need at least 2 maps") unless @maps >= 2;
my %args = (-min_num => 1, -min_percent => 100, -require_self => 1, -required => undef, @extra_args);
my $min_num = $args{-min_num};
if ($args{-min_percent}) {
my $mn = @maps / 100 * $args{-min_percent};
if ($mn > $min_num) {
$min_num = $mn;
}
}
my %required = map { $_ => 1 } $args{-required} ? @{$args{-required}} : ();
$required{$self} = 1 if ref($self) && $args{-require_self};
my @required = keys %required;
my %map_elements;
my %elements;
my %count;
foreach my $map (@maps) {
$map_elements{$map} = {};
foreach my $element ($map->get_elements) {
$map_elements{$map}->{$element} = 1;
$elements{$element} = $element;
$count{$element}++;
}
}
my @elements;
ELEMENT: while (my ($key, $value) = each %elements) {
$count{$key} >= $min_num or next;
foreach my $required (@required) {
exists $map_elements{$required}->{$key} or next ELEMENT;
}
push(@elements, $value);
}
return @elements;
}
=head2 MapI-specific methods
=cut
=head2 species
Title : species
Usage : my $species = $map->species;
Function: Get/Set Species for a map
Returns : L<Bio::Species> object
Args : (optional) Bio::Species
=cut
sub species{
my $self = shift;
$self->throw_not_implemented();
}
=head2 units
Title : units
Usage : $map->units('cM');
Function: Get/Set units for a map
Returns : units for a map
Args : units for a map (string)
=cut
sub units{
my $self = shift;
$self->throw_not_implemented();
}
=head2 type
Title : type
Usage : my $type = $map->type
Function: Get/Set Map type
Returns : String coding map type
Args : (optional) string
=cut
sub type {
my $self = shift;
$self->throw_not_implemented();
}
=head2 name
Title : name
Usage : my $name = $map->name
Function: Get/Set Map name
Returns : Map name
Args : (optional) string
=cut
sub name {
my $self = shift;
$self->throw_not_implemented();
}
=head2 length
Title : length
Usage : my $length = $map->length();
Function: Retrieves the length of the map.
It is possible for the length to be unknown for maps such as
Restriction Enzyme, will return 0 in that case
Returns : integer representing length of map in current units
will return undef if length is not calculateable
Args : none
=cut
sub length {
my $self = shift;
$self->throw_not_implemented();
}
1;
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